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Based on their heights, Ethan and Lyra (and presumably Kris as well) should be about eleven or twelve, Lucas should be ten or eleven, and Dawn should be ten. Don't take that as gospel, though. N is confirmed to be eighteen-to-twenty in Black and White.

Brock is canonically fifteen in the anime, so that's how old I imagine him to be in Generation I. Misty is harder to pinpoint, being canonically ten in the anime but twelve in The Electric Tale of Pikachu. Judging by her status as a Gym Leader, the way she speaks to Red on their first meeting...